Transepithelial cross-linking in keratoconus patients: confocal analysis.
Publisher: Lippincott Williams & Wilkins; PMID: 22940781;
Purpose: To analyze the modifications of the corneal layers after transepithelial (TE) corneal cross-linking (CXL).
Methods: Twenty eyes of 20 patients with progressive keratoconus were treated with TE-CXL (without epithelium debridement), and their corneas analyzed at different times, up to 18 months, by confocal microscopy using a Nidek Confoscan 4.
The TE-CXL procedure appears to be safe and effective at least up to 18 months. The absence of epithelium debridement (necessary in the classical technique) makes the procedure more comfortable for the patient, and allows the treatment of thinner corneas (between 360 and 400 μm) and problematic patients.La procedura totalmente computerizzata, consente la massima precisione di esecuzione migliorando sensibilmente la qualità della visione.
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Subjects: Corneal Stroma surgery; Cross-Linking Reagents therapeutic use; Debridement methods; Epithelium, Corneal surgery; Keratoconus diagnosis; Microscopy, Confocal methods; Adolescent: 13-18 years; Adult: 19-44 years; Young Adult: 19-24 years; All Child: 0-18 years; All Adult: 19+ years; Female; Male.